Pandora's Box turns every Strike and Defend in your deck into random cards. The moment you take it the deck transforms, instantly locking in the direction of the run. It is a full gamble, but no other relic gives you the scale of around 9 starter cards being swapped at once.
How Timing Affects Value
- Immediately after Act 1 is the best time. You still have most Strikes/Defends, so the transformation count is maximized
- From Act 2 onward many of those have been removed. Fewer cards transform
- A deck that aggressively removed cards sees less value. Conversely, a deck that prioritized adds can clean out remaining starter cards
Risk and Reward
- Transformed cards pull from the full character-specific pool at random
- Common through Rare are not evenly distributed — common and uncommon dominate
- Luck favors assembled combo parts, while bad luck scatters the deck's direction
- Even on a miss, transformed cards are usually stronger than Strike/Defend, so total busts are rare
Character Ratings
| Character |
Rating |
Comment |
| Ironclad |
A+ |
Strong overall pool with few losers. Pulling Strength pieces completes a damage deck instantly |
| Silent |
A |
Poison and discard lines hit god-tier but carry moderate miss risk |
| Defect |
A |
Orb pieces are great, but Lightning/Frost/Dark spread can leave a muddled deck |
| Necrobinder |
B+ |
Summon assembly is RNG. Balance between summon and sacrifice pieces matters |
| Regent |
B+ |
Depends on Star card alignment. Forge pieces rock, but hard to predict |