Pandora's Box

On obtain, transform all Strikes and Defends in your deck into random cards.

Pandora's Box transforms every Strike and Defend in your deck into a random card the moment you obtain it. Your deck changes dramatically in an instant, setting the direction of your run in one roll of the dice. It is a complete gamble, but the potential payoff — roughly 9 starting cards replaced simultaneously — is something no other relic can replicate.

How Timing Affects Value

• Taking it immediately after Act 1 is generally the most impactful timing. More Strikes and Defends remain at that point, maximizing the number of cards that transform.
• In Act 2 and beyond, you have often already removed Strikes and Defends, so fewer cards transform.
• In a deck that has aggressively removed starting cards, the value drops. In a deck that prioritized adding cards, it can clean up remaining starter cards all at once.

Risk and Reward

• Transformed cards are drawn randomly from the full character card pool.
• The distribution skews toward commons and uncommons rather than rares.
• A lucky roll can assemble combo pieces and complete a build instantly; a bad roll scatters unrelated cards and leaves the deck directionless.
• Even in the worst case, the new cards are generally stronger than Strikes and Defends, so a complete miss is rare.

Character Ratings

• Immediately after taking Pandora's Box, review your deck and rebuild around the direction the transformed cards suggest.
• If a clear synergy has emerged (multiple poison cards, multiple Strength cards, etc.), commit fully to that direction.
• If the results are scattered, switch to a goodstuff approach — add strong individual cards and remove the weakest results.
• When taken in Act 1, prioritize picking up cards that fill the gaps left in your deck for the rest of the run.